Journal of Pediatric Surgery
Volume 36, Issue 5 , Pages 777-779 , May 2001

Intestinal neuronal dysplasia: Results of treatment in 33 patients

Presented at the 32nd Annual Meeting of the Canadian Association of Paediatric Surgeons, Chateau Montebello, Quebec, Canada, September 15-18, 2000.

References 

  1. Meier-Ruge W. Uber ein Ekrankungsbild des colon mit Hirschsprung-Symptomatik. Vehr Dtsch Ges Pathol. 1971;55:506–510
  2. Fadda B, Maier WA, Meier-Ruge , et al.  Neuronale intestinal Dysplasie: Eine kritische 10-Jahres-Analyse klinischer und bioptischer diagnostik. Z Kinderchir. 1983;38:305–312
  3. Scharli AF. Neuronal intestinal dysplasia. Pediatric Surg Int. 1992;7:2–7
  4. Koletzko S, Jesch I, Faus-KeSler T, et al.  Rectal biopsy for diagnosis of intestinal dysplasia in children: A prospective multicentre study on inter-observer variation and clinical outcome. Gut. 1999;44:853–861
  5. Hatano M, Aoki T, Dezawa M, et al.  A novel pathogenesis of megacolon in NCX/HOX 11L1 deficient mice. J Clin Invest. 1997;100:795–801
  6. Shirisawa S, Yunker AMR, Roth KA, et al.  ENX (HOX 11L1) deficient mice develop myenteric neuronal hyperplasia and megacolon. Nat Med. 1997;3:646–650
  7. Puri P. Variant Hirschsprung's disease. J Pediatr Surg. 1997;32:149–157
  8. Puri P, Wester T. Intestinal Neuronal Dysplasia. Semin Pediatr Surg. 1998;7:181–186
  9. Kobayashi H, Hirakawa H, Puri P. What are the diagnostic criteria for Intestinal Neuronal Dysplasia?. Pediatr Surg Int. 1995;10:459–464
  10. Lumb PD, Moore L. Are giant ganglia a reliable marker of intestinal neuronal dysplasia type B (IND B). Virchow's Arch. 1998;432:103–106
  11. Lake BD. Intestinal Neuronal Dysplasia. Why does it only occur in parts of Europe?. Virchows Arch. 1995;426:537–539
  12. Moore SW, Laing D, Melis J, et al.  Secondary effects of prolonged intestinal obstruction on the enteric nervous system in the rat. J Pediatr Surg. 1993;28:1196–1199
  13. Schmittenbecher PP, Gluck M, Wiebecke B, et al.  Clinical long-term follow-up results in Intestinal Neuronal Dysplasia (IND). Eur J Pediatr Surg. 2000;10:17–22
  14. Wester T, O'Briain DS, Puri P. Notable postnatal alterations in the myenteric plexus of normal human bowel. Gut. 1999;44:666–674
  15. Wester T, O'Briain S, Puri P. Morphometric aspects of the submucous plexus in whole-mount preparations of normal human distal colon. J Pediatr Surg. 1998;33:619–622
  16. Munakata K, Morita K, Okabe I, et al.  Clinical and histologic studies of neuronal intestinal dysplasia. J Pediatr Surg. 1985;20:231–235
  17. Csury L, Peña A. Intestinal neuronal dysplasia. Myth or reality? Literature review. Pediatr Surg Int. 1995;10:441–446
  18. Ure BM, Holschneider AM, Schulten D, et al.  Clinical impact of intestinal neuronal malformations: A prospective study in 141 patients. Pediatr Surg Int. 1997;12:377–382

 Address reprint requests to Mr Prem Puri, MS, FRCS, FRCS(Ed), FACS, Director of Research, The Children's Research Centre, Our Lady's Hospital for Sick Children, Crumlin, Dublin 12, Ireland.

PII: S0022-3468(01)35062-5

doi: 10.1053/jpsu.2001.22959

Journal of Pediatric Surgery
Volume 36, Issue 5 , Pages 777-779 , May 2001