Journal of Pediatric Surgery
Volume 36, Issue 7 , Pages 980-984 , July 2001

Surfactant and inhaled nitric oxide in rats alleviate acute lung injury induced by intestinal ischemia and reperfusion

References 

  1. Caty MG, Guice KS, Oldham KT, et al.  Evidence for tumor necrosis factor-induced pulmonary microvascular injury after intestinal ischemia-reperfusion injury. Ann Surg. 1990;212:694–700
  2. Koike K, Moore FA, Moore EE, et al.  Endotoxin after gut ischemia/reperfusion causes irreversible lung injury. J Surg Res. 1992;52:656–662
  3. Lewis JF, Jobe AH. Surfactant and acute respiratory distress syndrome. Am Rev Respir Dis. 1993;147:218–233
  4. Zhu GF, Sun B, Niu SF, et al.  Combined surfactant therapy and inhaled nitric oxide in rabbits with oleic acid-induced acute respiratory distress syndrome. Am J Respir Crit Care Med. 1998;158:437–443
  5. Zhou ZH, Sun B, Lin K, et al.  Prevention of rabbit acute lung injury by surfactant, inhaled nitric oxide and pressure support ventilation. Am J Respir Crit Care Med. 2000;161:581–588
  6. Zhao DH, Sun B, Wu ZH, et al.  Mitigation of endotoxin-induced acute lung injury in ventilated rabbits by surfactant and inhaled nitric oxide. Intens Care Med. 2000;26:229–238
  7. Bartlett GB. Phosphorous assay in column chromatography. J Biol Chem. 1959;234:466–468
  8. Mason RJ, Nellenbogen J, Clements JA. Isolation of disaturated phosphatidyl-choline with osmium tetroxide. J Lipid Res. 1976;17:281–284
  9. Lowry OH, Rosebrough NJ, Farr AL, et al.  Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265–275
  10. Ennema JJ, Kobayashi T, Robertson B, et al.  Inactivation of exogenous surfactant in experimental respiratory failure induced by hyperoxia. Acta Anaesthesiol Scand. 1988;32:665–671
  11. Terada LS, Dormish JJ, Shanley PF, et al.  Circulating xanthine oxidase increases following intestinal ischemia-reperfusion and mediates lung neutrophil sequestration. Am J Physiol. 1992;263:L394–L401
  12. Papparella A, DeLuca FG, Oyer CE, et al.  Ischemia-reperfusion injury in the intestines of newborn pigs. Pediatr Res. 1997;42:180–188
  13. Terada LS, Mahr NN, Jacobson ED. Nitric oxide decreases lung injury after intestinal ischemia. J Appl Physiol. 1996;81:2456–2460
  14. Walker NW, Kinter MT, Roberts RJ, et al.  Nitric oxide-induced cytotoxicity: Involvement of cellular resistance to oxidative stress and the role of glutathione in protection. Pediatr Res. 1995;37:41–49
  15. Koksoy C, Kuzu MA, Ergun H, et al.  Intestinal ischemia and reperfusion impairs vasomotor functions of pulmonary vascular bed. Ann Surg. 2000;231:105–111
  16. Mitsuoka H, Salurai T, Unno N, et al.  Intravital laser confocal microscope of pulmonary edema resulting from intestinal ischemia-reperfusion injury in the rat. Crit Care Med. 1999;27:1862–1868
  17. Pittet JF, Mackersie RC, Martin TR, et al.  Biological markers of acute lung injury: Prognostic and pathogenetic significance. Am J Respir Crit Care Med. 1997;155:1187–1205
  18. Sison C, Bry C, Sephus J, et al.  Effects of inhaled nitric oxide and surfactant treatment on lung function and pulmonary hemodynamics in bronchoalveolar-lavage-induced respiratory failure. Pediatr Pulmonol. 2000;29:202–209

 Supported in part by Shanghai Education and Development Foundation (Grant No. 97SG14), Shanghai Bureau of Health Research Funds (No. 97BR023, 97BR024, 99ZYI001), Ministry of Education Research Funds, and China Medical Board of New York (No. 95-620). Bo Sun is a recipient of the Cheung Kong Scholars Programme, Ministry of Education, P.R. China.

☆☆ Address reprint requests to Bo Sun, MD, PhD, Children's Hospital of Fudan University Medical Center, (Formerly Shanghai Medical University), 183 Feng Lin Rd, Shanghai 200032, P.R. China.

PII: S0022-3468(01)36730-1

doi: 10.1053/jpsu.2001.24721

Journal of Pediatric Surgery
Volume 36, Issue 7 , Pages 980-984 , July 2001