Journal of Pediatric Surgery
Volume 40, Issue 1 , Pages 251-255 , January 2005

Results of multimodal treatment for desmoplastic small round cell tumors

Presented at the 35th Annual Meeting of the American Pediatric Surgical Association, Ponte Vedra, Florida, May 27-30, 2004.

References 

  1. La Quaglia MP, Brennan MF. The clinical approach to desmoplastic small round cell tumor. Surg. Oncol. 2000;9:77–81
  2. Gerald WL, Rosai J. Desmoplastic small cell tumor with multi-phenotypic differentiation. Zentralbl. Pathol. 1993;139:141–151
  3. Schwarz RE, Gerald WL, Kushner BH, et al. Desmoplastic small round cell tumors: prognostic indicators and results of surgical management. Ann. Surg. Oncol. 1998;5:416–422
  4. Rodriguez E, Sreekantaiah C, Gerald W, et al. A recurring translocation, t(11;22)(p13;q11.2), characterizes intra-abdominal desmoplastic small round-cell tumors. Cancer Genet. Cytogenet. 1993;69:17–21
  5. Sawyer JR, Tryka AF, Lewis JM. A novel reciprocal chromosome translocation t(11;22)(p13;q12) in an intraabdominal desmoplastic small round-cell tumor. Am. J. Surg. Pathol. 1992;16:411–416
  6. Liu J, Nau MM, Zucman-Rossi J, et al. LINE-I element insertion at the t(11;22) translocation breakpoint of a desmoplastic small round cell tumor. Genes, Chromosomes & Cancer. 1997;18:232–239
  7. Gerald WL, Ladanyi M, de Alava E, et al. Clinical, pathologic, and molecular spectrum of tumors associated with t(11;22)(p13;q12): desmoplastic small round-cell tumor and its variants EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma. J. Clin. Oncol. 1998;16:3028–3036
  8. Lae ME, Roche PC, Jin L, et al. Desmoplastic small round cell tumor: a clinicopathologic, immunohistochemical, and molecular study of 32 tumors. Am. J. Surg. Pathol. 2002;26:823–835
  9. Kushner BH, LaQuaglia MP, Wollner N, et al. Desmoplastic small round-cell tumor: prolonged progression-free survival with aggressive multimodality therapy. J. Clin. Oncol. 1996;14:1526–1531
  10. Lee SB, Kolquist KA, Nichols K, et al. The EWS-WT1 translocation product induces PDGFA in desmoplastic small round-cell tumour. Nat. Genet. 1997;17:309–313
  11. Ito E, Honma R, Imai J, et al. A tetraspanin-family protein, T-cell acute lymphoblastic leukemia-associated antigen 1, is induced by the Ewing's sarcoma-Wilms' tumor 1 fusion protein of desmoplastic small round-cell tumor. Am. J. Pathol. 2003;163:2165–2172
  12. Wong JC, Lee SB, Bell MD, et al. Induction of the interleukin-2/15 receptor beta-chain by the EWS-WT1 translocation product. Oncogene. 2002;21:2009–2019
  13. Adamson PC, Blaney SM, Widemann BC, et al. Pediatric phase I trial and pharmacokinetic study of the platelet-derived growth factor (PDGF) receptor pathway inhibitor SU101. Cancer Chemother. Pharmacol. 2004;536:482–488
  14. Modak S, Gerald W, Cheung NK. Disialoganglioside GD2 and a novel tumor antigen: potential targets for immunotherapy of desmoplastic small round cell tumor. Med. Pediatr. Oncol. 2002;39:547–551
  15. Modak S, Kramer K, Gultekin SH, et al. Monoclonal antibody 8H9 targets a novel cell surface antigen expressed by a wide spectrum of human solid tumors. Cancer Res. 2001;61:4048–4054

PII: S0022-3468(04)00649-9

doi: 10.1016/j.jpedsurg.2004.09.046

Journal of Pediatric Surgery
Volume 40, Issue 1 , Pages 251-255 , January 2005

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