Journal of Pediatric Surgery
Volume 44, Issue 8 , Pages 1611-1620 , August 2009

Effect of prenatal tetrandrine administration on transforming growth factor-β1 level in the lung of nitrofen-induced congenital diaphragmatic hernia rat model

Received 24 July 2008 ,Revised 8 September 2008 ,Accepted 21 September 2008.

References 

  1. Chapin CJ, Ertsey R, Yoshizawa J, et al. Congenital diaphragmatic hernia, tracheal occlusion, thyroid transcription factor-1, and fetal pulmonary epithelial maturation. Am J Physiol Lung Cell Mol Physiol. 2005;289:L44–L52
  2. Colvin J, Bower C, Dickinson JE, et al. Outcomes of congenital diaphragmatic hernia: a population-based study in Western Australia. Pediatrics. 2005;116:e356–e363
  3. Grethel EJ, Farrell J, Ball R, et al. Congenital diaphragmatic hernia associated with spinal anomalies. Obstet Gynecol. 2007;109:485–488
  4. Folkesson HG, Chapin CJ, Beard LL, et al. Congenital diaphragmatic hernia prevents absorption of distal air space fluid in late-gestation rat fetuses. Am J Physiol Lung Cell Mol Physiol. 2006;290:L478–L484
  5. Robinson PD, Fitzgerald DA. Congenital diaphragmatic hernia. Paediatr Respir Rev. 2007;8:323–334
  6. You LR, Takamoto N, Yu CT, et al. Mouse lacking COUP-TFII as an animal model of Bochdalek-type congenital diaphragmatic hernia. Proc Natl Acad Sci U S A. 2005;102:16351–16356
  7. Harrison MR. In: The unborn patient: fetal diagnosis and treatment. Philadelphia (Pa): Saunders; 1990;p. 295–319
  8. Allan DW, Greer JJ. Pathogenesis of nitrofen-induced congenital diaphragmatic hernia in fetal rats. J Appl Physiol. 1997;83:338–347
  9. Guilbert TW, Gebb SA, Shannon JM. Lung hypoplasia in the nitrofen model of congenital diaphragmatic hernia occurs early in development. Am J Physiol Lung Cell Mol Physiol. 2000;279:L1159–L1171
  10. Jay PY, Bielinska M, Erlich JM, et al. Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects. Dev Biol. 2007;301:602–614
  11. Richard K, Jason L, Julie D, et al. Dual-hit hypothesis explains pulmonary hypoplasia in the nitrofen model of congenital diaphragmatic hernia. Am J Pathol. 2000;156:1299
  12. Leinwand MJ, Tefft JD, Zhao J, et al. Nitrofen inhibition of pulmonary growth and development occurs in the early embryonic mouse. J Pediatr Surg. 2002;37:1263–1268
  13. Kitano Y. Prenatal intervention for congenital diaphragmatic hernia. Semin Pediatr Surg. 2007;16:101–108
  14. Doné E, Gucciardo L, Van Mieghem T, et al. Prenatal diagnosis, prediction of outcome and in utero therapy of isolated congenital diaphragmatic hernia. Prenat Diagn. 2008;28(7):581–591
  15. Ruano R, Aubry MC, Dumez Y, Zugaib M, Benachi A. Predicting neonatal deaths and pulmonary hypoplasia in isolated congenital diaphragmatic hernia using the sonographic fetal lung volume-body weight ratio. AJR Am J Roentgenol. 2008;190:1216–1219
  16. Xie QM, Tang HF, Chen JQ, et al. Pharmacological actions of tetrandrine in inflammatory pulmonary diseases. Acta Pharmacol Sin. 2002;23:1107–1113
  17. Liu B, Wang T, Qian X, et al. Anticancer effect of tetrandrine on primary cancer cells isolated from ascites and pleural fluids. Cancer Lett. 2008;268:166–175
  18. Oh SH, Lee BH. Induction of apoptosis in human hepatoblastoma cells by tetrandrine via caspase-dependent Bid cleavage and cytochrome C release. Biochem Pharmacol. 2003;66:725–731
  19. Liu W, Feng J, Jia H, et al. Effect of prenatal tetrandrine therapy on pulmonary vascular structural remodeling in the nitrofen-induced CDH rat model. Chin Med J. 2000;113:813–816
  20. Lin H, Wang Y, Xiong Z, et al. Effect of antenatal tetrandrine administration on endothelin-1 and epidermal growth factor levels in the lungs of rats with experimental diaphragmatic hernia. J Pediatr Surg. 2007;42:1644–1651
  21. Belik J, Davidge ST, Zhang W, et al. Airway smooth muscle changes in the nitrofen-induced congenital diaphragmatic hernia rat model. Pediatr Res. 2003;53:737
  22. Kurnar VH, Ryan RM. Growth factors in fetal and neonatal lung. Front Biosci. 2004;9:464–480
  23. Oue T, Shima H, Guarino N, et al. Antenatal dexamethasone administration increases fetal lung DNA synthesis and RNA and protein content in nitrofen-induced congenital diaphragmatic hernia in rats. Pediatr Res. 2000;48:789–793
  24. Serra R, Pelton RW, Moses HL. TGF beta 1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures. Development. 1994;120:2153–2161
  25. Zhou L, Dey CR, Wert SE, et al. Arrested lung morphogenesis in transgenic mice bearing an SP-C TGF-beta 1 chimeric gene. Dev Biol. 1985;175:227–238
  26. Zhao J, Bu D, Lee M, et al. Abrogation of transforming growth factor-beta type II receptor stimulates embryonic mouse lung branching morphogenesis in culture. Dev Biol. 1996;180:242–257
  27. Oue T, Shima H, Taira Y, et al. Administration of antenatal glucocorticoids upregulates peptide growth factor gene expression in nitrofen-induced congenital diaphragmatic hernia in rats. J Pediatr Surg. 2000;35:109–112
  28. Leinwand MJ, Zhao J, Tefft JD. Murine nitrofen-induced pulmonary hypoplasia does not involve induction of TGF-beta signaling. J Pediatr Surg. 2002;37:1123–1127
  29. Babiuk RP, Greer JJ. Diaphragm defects occur in a CDH hernia model independently of myogenesis and lung formation. Am J Physiol Lung Cell Mol Physiol. 2002;283:L1310–L1314
  30. Gonzalez-Reyes S, Martinez L, Martinez-Calonge W, et al. Effects of nitrofen and vitamins A, C and E on maturation of cultured human H441 pneumocytes. Biol Neonate. 2006;90:9–16
  31. Harrison MR, Keller RL, Hawgood SB, et al. A randomized trial of fetal endoscopic tracheal occlusion for severe fetal congenital diaphragmatic hernia. N Engl J Med. 2003;349:1916–1924
  32. Bütter A, Bratu I, Flageole H, et al. Fetal tracheal occlusion in lambs with congenital diaphragmatic hernia: role of exogenous surfactant at birth. Pediatr Res. 2005;58:689–694

PII: S0022-3468(08)00814-2

doi: 10.1016/j.jpedsurg.2008.09.021

Journal of Pediatric Surgery
Volume 44, Issue 8 , Pages 1611-1620 , August 2009