Journal of Pediatric Surgery
Volume 45, Issue 3 , Pages 499-506 , March 2010

A new rat model of prenatal bowel obstruction: development and early assessment

  • Laurent M. Fourcade

      Affiliations

    • Pediatric Surgery Department, Centre Hospitalier Universitaire de Limoges, Hôpital de la Mère et de L'enfant, 87000 Limoges, France
    • Corresponding Author InformationCorresponding author. Université de Limoges, Faculté de Médecine, EA4021, 2 Rue du Dr Marcland, 87025 Limoges Cedex, France.
    • ,
  • Yoanne Mousseau

      Affiliations

    • Molecular Biology Department, Université de Limoges, Faculté de Médecine, EA4021, 87025 Limoges Cedex, France
    • ,
  • Frédérique Sauvat

      Affiliations

    • Pediatric Surgery Department, Hôpital Necker, 75015 Paris, France
    • ,
  • Naziha Khen-Dunlop

      Affiliations

    • Inserm U793, faculté de médecine, université Paris-Descartes, 156, rue de Vaugirard, 75015 Paris, France
    • ,
  • Nadine Cerf-Bensussan

      Affiliations

    • Inserm U793, faculté de médecine, université Paris-Descartes, 156, rue de Vaugirard, 75015 Paris, France
    • ,
  • Sabine Sarnacki

      Affiliations

    • Inserm U793, faculté de médecine, université Paris-Descartes, 156, rue de Vaugirard, 75015 Paris, France
    • ,
  • Franck G. Sturtz

      Affiliations

    • Molecular Biology Department, Université de Limoges, Faculté de Médecine, EA4021, 87025 Limoges Cedex, France

Received 11 March 2009 ,Revised 9 June 2009 ,Accepted 11 July 2009.

References 

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  2. Pickard LR, Santoro S, Wyllie RG, et al. Histochemical studies of experimental fetal intestinal obstruction. J Pediatr Surg. 1981;16:256–260
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  13. Kitano Y, Yang EY, von Allmen D, et al. Tracheal occlusion in the fetal rat: a new experimental model for the study of accelerated lung growth. J Pediatr Surg. 1998;33:1741–1744
  14. Baird R, Khan N, Flageole H, et al. The effect of tracheal occlusion on lung branching in the rat nitrofen CDH model. J Surg Res. 2007;
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  16. Trier J, Moxey P. Morphogenesis of the small intestine during fetal development. Ciba Found Symp. 1979;70:3–29
  17. Mathan M, Moxey PC, Trier JS. Morphogenesis of fetal rat duodenal villi. Am J Anat. 1976;146:73–92
  18. Mulvihill SJ, Stone MM, Debas HT, et al. The role of amniotic fluid in fetal nutrition. J Pediatr Surg. 1985;20:668–672
  19. Trahair JF, Harding R. Ultrastructural anomalies in the fetal small intestine indicate that fetal swallowing is important for normal development: an experimental study. Virchows Arch A Pathol Anat Histopathol. 1992;420:305–312
  20. Buchmiller TL, Gregg J, Rivera FA, et al. Effect of esophageal ligation on the development of fetal rabbit intestinal lactase. J Pediatr Surg. 1993;28:1473–1477
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PII: S0022-3468(09)00591-0

doi: 10.1016/j.jpedsurg.2009.07.031

Journal of Pediatric Surgery
Volume 45, Issue 3 , Pages 499-506 , March 2010

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