Meta-analysis: the clinical features of the duodenal duplication cyst

Chen, Jeng-Jung; Lee, Hung-Chang; Yeung, Chun-Yan; Chan, Wai-Tao; Jiang, Chuen-Bin; Sheu, Jin-Cherng

doi:10.1016/j.jpedsurg.2010.01.010

« Previous Next »Journal of Pediatric Surgery
Volume 45, Issue 8 , Pages 1598-1606, August 2010

Meta-analysis: the clinical features of the duodenal duplication cyst

Jeng-Jung Chen
- Department of Pediatrics, Mackay Memorial Hospital, Taipei 10449, Taiwan
Hung-Chang Lee
- Department of Pediatrics, Mackay Memorial Hospital, Taipei 10449, Taiwan
- Department of Pediatrics, Taipei Medical University, Taipei 10449, Taiwan
- Corresponding author. Taipei City 10449, Taiwan. Tel.: +886 2 2543 3535x2435; fax: +886 2 2543 3642.
Chun-Yan Yeung
- Department of Pediatrics, Mackay Memorial Hospital, Taipei 10449, Taiwan
- Mackay Medicine, Nursing and Management College, Taipei 10449, Taiwan
Wai-Tao Chan
- Department of Pediatrics, Mackay Memorial Hospital, Taipei 10449, Taiwan
Chuen-Bin Jiang
- Department of Pediatrics, Mackay Memorial Hospital, Taipei 10449, Taiwan
Jin-Cherng Sheu
- Department of Pediatric Surgery, Mackay Memorial Hospital, Taipei 10449, Taiwan

Received 24 October 2009; received in revised form 5 January 2010; accepted 6 January 2010.

Abstract

Background

Duplication cyst of the duodenum is rare. This study describes a case of duodenal duplication and evaluates its clinical features through a literature review.

Methods

A case of duodenal duplication is reported, and related articles published from 1999 to 2009 on PubMed were reviewed. Clinical manifestations, diagnostic examinations, and methods of management were analyzed.

Results

Including this report, there had been 38 citations in literature that provide adequate descriptions of 47 cases of duodenal duplication cysts. Nineteen (40.4%) were discovered before 10 years of age, whereas 10 (21.3%) were found in the second decade. The remaining 18 patients (38.3%) were older than 20 years. The case number decreased as age increased. Overall, 80% of cases presented with abdominal pain, and 53% were complicated with pancreatitis.

Conclusions

The most common symptom in duodenal duplication cysts is abdominal pain with or without nausea or vomiting. The most common complication is pancreatitis. Differential diagnoses of pancreatitis, hepatitis, cholestasis, or intussusception should include duplication cyst of the duodenum.

Key words: Cholestasis, Duodenum, Duplication cyst, Intussusception, Pancreatitis