Journal of Pediatric Surgery
Volume 31, Issue 4 , Pages 498-502 , April 1996

A new rodent experimental model of esophageal atresia and tracheoesophageal fistula: Preliminary report

  • Juan A. Diez-Pardo

      Affiliations

    • Department of Pediatric Surgery, Hospital “La Paz”, Universidad Auto´noma, Madrid, Spain
    • the Department of Pathology, Hospital do Meixoeiro, Vigo, Spain.
    • ,
  • Qi Baoquan

      Affiliations

    • Department of Pediatric Surgery, Hospital “La Paz”, Universidad Auto´noma, Madrid, Spain
    • the Department of Pathology, Hospital do Meixoeiro, Vigo, Spain.
    • Dr Baoquan is an International Research Fellow supported by an FIS grant.
    • ,
  • C. Navarro

      Affiliations

    • Department of Pediatric Surgery, Hospital “La Paz”, Universidad Auto´noma, Madrid, Spain
    • the Department of Pathology, Hospital do Meixoeiro, Vigo, Spain.
    • ,
  • Juan A. Tovar

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Juan A. Tovar, MD, PhD, Department of Surgery, Hospital Infantil “La Paz”, Paseo de la Castellana 261, 28046 Madrid, Spain.
    • Department of Pediatric Surgery, Hospital “La Paz”, Universidad Auto´noma, Madrid, Spain
    • the Department of Pathology, Hospital do Meixoeiro, Vigo, Spain.

Reference 

  1. Gross RE. In: ed 4. The Surgery of Infancy and Childhood. Philadelphia, PA: Saunders; 1953;p. 99–118
  2. Chang KS, Chang JHT. Animal models of pediatric surgical diseases. Pediatr Surg Int. 1994;9:307–322
  3. Kleckner SC, Pringle KC, Clark EB. The effect of chick embryo hyperflexion on tracheoesophageal development. J Pediatr Surg. 1984;19:340–344
  4. Warkany J, Roth TB, Wilson JG. Multiple congenital malformations: A consideration of etiologic factors. Pediatrics. 1948;1:462–471
  5. Kalter H, Warkany J. Congenital malformations in imbred strains of mice induced by riboflavin deficient, galactoflavin-containing diets. J Exp Zool. 1957;136:531–542
  6. Thompson DJ, Molello JA, Strebing RJ, et al. Teratogenicity of Adriamycin and Daunomycin in the rat and rabbit. Teratology. 1978;17:151–158
  7. Carter SK. Adriamycin—A review. J Natl Cancer Inst. 1975;55:1265–1274
  8. Roboz J, Gleicher N, Wu K, et al. Does doxurubicin cross the placenta?. Lancet. 1979;2:1382–1383
  9. Vicente Garci´a V, San Miguel J, Lo´pez Borrasca A. Adriamicina y embarazo. Sangre. 1981;26:129;(letter)
  10. Karp GI, Von Oeyen P, Valone F, et al. Doxorubicin in pregnancy: Possible transplacental passage. Cancer Treat Rep. 1983;67:773–777
  11. D'Incalci M, Broggini M, Buscaglia M, et al. Transplacental passage of doxorubicin. Lancet. 1983;1:75
  12. Tobias JS, Bloom HJG. Doxorubicin in pregnancy. Lancet. 1980;1:776
  13. Vig BK. Chromosome aberrations induced in human leucocytes by the antileukemic antibiotic adriamycin. Cancer Res. 1971;31:32–38
  14. Pierro A, Cozzi F, Colarossi G, et al. Does fetal gut obstruction cause hydramnios and growth retardation?. J Pediatr Surg. 1987;22:454–457
  15. Kluth D, Steding G, Seidl W. The embryology of foregut malformations. J Pediatr Surg. 1987;22:389–393
  16. Sutliff KS, Hutchins GM. Septation of the respiratory and digestive tracts in human embryos: Crucial role of the tracheoesophageal sulcus. Anat Rec. 1994;238:237–247

 Presented at the 42nd Annual International Congress of the British Association of Paediatric Surgeons, Sheffield, England, July 25–28, 1995.

 Supported in part by Grant 93/0031-01 and 94/0190 of the Fondo de Investigacio´n Sanitaria.

PII: S0022-3468(96)90482-0

Journal of Pediatric Surgery
Volume 31, Issue 4 , Pages 498-502 , April 1996

Article Tools