Journal of Pediatric Surgery
Volume 32, Issue 1 , Pages 41-43 , January 1997

Hyaluronic acid of wound fluid in adult and fetal rabbits

  • Toshio Sawai

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Toshio Sawai, MD, Department of Pediatric Surgery, Osaka University Medical School, 2-2 Yamada-oka, Suita, Osaka 565, Japan.
    • Department of Pediatric Surgery, Osaka University, Medical School, Osaka, Japan.
    • Department of Biochemistry, Osaka University, Medical School, Osaka, Japan.
    • the Institute for Molecular Science of Medicine, Aichi Medical University, Aichi, Japan.
    • ,
  • Noriaki Usui

      Affiliations

    • Department of Pediatric Surgery, Osaka University, Medical School, Osaka, Japan.
    • Department of Biochemistry, Osaka University, Medical School, Osaka, Japan.
    • the Institute for Molecular Science of Medicine, Aichi Medical University, Aichi, Japan.
    • ,
  • Kinya Sando

      Affiliations

    • Department of Pediatric Surgery, Osaka University, Medical School, Osaka, Japan.
    • Department of Biochemistry, Osaka University, Medical School, Osaka, Japan.
    • the Institute for Molecular Science of Medicine, Aichi Medical University, Aichi, Japan.
    • ,
  • Yuichi Fukui

      Affiliations

    • Department of Pediatric Surgery, Osaka University, Medical School, Osaka, Japan.
    • Department of Biochemistry, Osaka University, Medical School, Osaka, Japan.
    • the Institute for Molecular Science of Medicine, Aichi Medical University, Aichi, Japan.
    • ,
  • Shinkichi Kamata

      Affiliations

    • Department of Pediatric Surgery, Osaka University, Medical School, Osaka, Japan.
    • Department of Biochemistry, Osaka University, Medical School, Osaka, Japan.
    • the Institute for Molecular Science of Medicine, Aichi Medical University, Aichi, Japan.
    • ,
  • Akira Okada

      Affiliations

    • Department of Pediatric Surgery, Osaka University, Medical School, Osaka, Japan.
    • Department of Biochemistry, Osaka University, Medical School, Osaka, Japan.
    • the Institute for Molecular Science of Medicine, Aichi Medical University, Aichi, Japan.
    • ,
  • Naoyuki Taniguchi

      Affiliations

    • Department of Pediatric Surgery, Osaka University, Medical School, Osaka, Japan.
    • Department of Biochemistry, Osaka University, Medical School, Osaka, Japan.
    • the Institute for Molecular Science of Medicine, Aichi Medical University, Aichi, Japan.
    • ,
  • Naoki Itano

      Affiliations

    • Department of Pediatric Surgery, Osaka University, Medical School, Osaka, Japan.
    • Department of Biochemistry, Osaka University, Medical School, Osaka, Japan.
    • the Institute for Molecular Science of Medicine, Aichi Medical University, Aichi, Japan.
    • ,
  • Koji Kimata

      Affiliations

    • Department of Pediatric Surgery, Osaka University, Medical School, Osaka, Japan.
    • Department of Biochemistry, Osaka University, Medical School, Osaka, Japan.
    • the Institute for Molecular Science of Medicine, Aichi Medical University, Aichi, Japan.

References 

  1. Burrington JD. Wound healing in the fetal lamb. J Pediatr Surg. 1971;6:523–528
  2. Rowsell AR. The intra-uterine healing of foetal muscle wounds. Br J Plast Surg. 1984;37:635–642
  3. Hallock GG. Inutero cleft lip repair in mice. Plast Reconstr Surg. 1985;75:785–788
  4. Adzick NS, Harrison MR, Glick PL, et al.  Comparison of fetal, newborn and adult wound healing by histologic, enzymehistochemical and hydroxyploline determinations. J Pediatr Surg. 1985;20:315–319
  5. Krummel TM, Nelson JM, Diegelmann RF, et al.  Fetal response to injury in the rabbit. J Pediatr Surg. 1987;22:640–644
  6. Lindbald WJ, Diegelmann RF. Quantitations of hydroxyproline isomers in acid hydrolysates by high performance liquid chromatography. Anal Biochem. 1984;138:390–395
  7. Tengblad A. Quantitative analysis of hyaluronate in nanogram amounts. Biochem J. 1980;185:101–105
  8. Levenson SM, Geever EF, Crowley LV, et al.  The healing of rat skin wounds. Ann Surg. 1965;161:293–298
  9. Doillon CJ, Dunn MG, Bender E, et al.  Collagen fiber formation in repair tissue: Development of strength and toughness. Collagen Rel Res. 1985;5:481–492
  10. Longaker MT, Whitby Dj, Adzick NS, et al.  Studies in fetal wound healing, IV. Second and early third trimester fetal wounds demonstrate rapid collagen deposition without scar formation. J Pediatr Surg. 1990;25:63–69
  11. Burd DAR, Longaker MT, Adzick NS, et al.  Foetal wound healing in a large animal model: The deposition of collagen is confirmed. Br J Plast Surg. 1990;43:571–577
  12. Bertolami CN, Donoff RB. Hyaluronidase activity during open wound healing in rabbits. J Surg Res. 1978;25:256–259
  13. Bertolami CN, Donoff RB. The effect of skin grafting upon prolyl hydroxylase and hyaluronidase activities in mammalian wound repair. J Surg Res. 1979;27:359–366
  14. Bertolami CN, Donoff RB. Identification, characterization and partial purification of mammalian skin wound hyaluronidase. J Invest Dermatol. 1982;79:417–421
  15. Mast BA, Haynes JH, Krummel TM, et al.  In vivo degradation of fetal wound hyaluronic acid results in increased fibroplasia, collagen deposition and neovascularization. Plast Reconstr Surg. 1992;89:503–509
  16. Underhill CB, Toole BP. Binding of hyaluronate to the surface of cultured cells. Cell Biol. 1979;82:475–484
  17. Underhill CB, Toole BP. Physical characteristics of hyaluronate binding to the surface of simian virus 40-transformed 3T3 cells. J Biol Chem. 1980;255:4544–4549
  18. Underhill CB, Toole BP. Receptors for hyaluronate on the surface of parent and virus-transformed cell lines. Exp Cell Res. 1981;131:419–423
  19. Knudson CB, Toole BP. Changes in the pericellular matrix during differentiation of limb bud mesoderm. Dev Biol. 1985;112:308–318
  20. McGary CT, Raja RH, Weigel PH. Endocytosis of hyaluronic acid by rat liver endothelial cells. Evidence for receptor recycling. Biochem J. 1989;257:875–884
  21. Yoneda M, Suzuki S, Kimata K. Hyaluronic acid associated with the surfaces of cultured fibroblasts is linked to a serum derived 85-kDa protein. J Biol Chem. 1990;265:5247–5257
  22. Pierce GF, Mustone TA, Deuel TF. Transforming growth factor β induces increased directed cellular migration and tissue repair in rats. In:  Barbul A,  Pines E editor. Growth Factors and Other Aspects of Wound Healing: Biological and Clinical Applications. New York, NY: Wiley-Liss; 1988;p. 93–102
  23. Roberts AB, Sporn MB, Assoian RK, et al.  Transforming growth factor type beta: Rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. In: (ed 3). Proc Natl Acad Sci U S A. 83:1986;p. 4167–4171
  24. Krummel TM, Michna BA, Thomas BL, et al.  Transforming growth factor-β induces fibrosis in fetal wound model. J Pediatr Surg. 1988;23:647–652
  25. Turley EA. The role of cell-associated hyaluronan-binding protein in fibroblast behavior. In: (ed 3). Ciba Found Symp. 143:1989;p. 121–133

☆ Presented at the 29th Annual Meeting of the Pacific Association of Pediatric Surgeons, Singapore, May 12–15, 1996.

PII: S0022-3468(97)90089-0

Journal of Pediatric Surgery
Volume 32, Issue 1 , Pages 41-43 , January 1997

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