Case Reports| Volume 37, ISSUE 10, P1488-1490, October 2002

Long-term survival after spontaneous rupture of a malignant rhabdoid tumor of the liver


      A 13-month-old girl presented with a large malignant rhabdoid liver tumor that ruptured soon after admission. Six years after an emergency right hepatectomy and subsequent chemotherapy (ifosfamide, vincristine, and actinomycin D), she remains well and disease free. Previously, these rare tumors invariably have been fatal and resistant to multimodal therapy. This is the first report of long-term survival of a patient with a malignant rhabdoid liver tumor. J Pediatr Surg 37:1488-1490. Copyright 2002, Elsevier Science (USA). All rights reserved.


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        • Stringer MD
        Liver tumors.
        Semin Pediatr Surg. 2000; 9: 196-208
        • Gonzalez-Crussi F
        • Goldschmidt RA
        • Hsueh W
        • et al.
        Infantile sarcoma with intracytoplasmic filamentous inclusions. Distinctive tumour of possible histiocytic origin.
        Cancer. 1982; 49: 2365-2375
        • Scheimberg I
        • Cullinane C
        • Kelsey A
        • et al.
        Primary hepatic malignant tumour with rhabdoid features. A histological, immunocytochemical and electron microscopic study of four cases and review of literature.
        Am J Surg Pathol. 1996; 20: 1394-1400
        • Beckwith JB
        • Palmer NF
        Histopathology and prognosis of Wilms tumour: Results from the first national Wilms' Tumor Study.
        Cancer. 1978; 41: 1937-1948
        • Gururangan S
        • Bowman LC
        • Parham DM
        • et al.
        Primitive extracranial rhabdoid tumours. Clinicopathologic features and response to Ifosfamide.
        Cancer. 1993; 71: 2653-2659
        • Kelly DM
        • Jones M
        • Humphreys S
        • et al.
        Spontaneous rupture of a malignant rhabdoid tumour of the liver.
        Pediatr Surg Int. 1998; 14: 111-112
        • Jiminez-Heffernan JA
        • Lopez-Ferrer O
        • Burgos E
        • et al.
        Pathological case of the month. Primary hepatic malignant tumour with rhabdoid features.
        Arch Pediatr Adolesc Med. 1998; 152: 509-510
        • Donner LR
        • Rao A
        • Truss LM
        • et al.
        Translocation (8;13)(q24.2;q33) in a malignant rhabdoid tumor of the liver.
        Cancer Genet Cytogenet. 2000; 116: 153-157
        • Weyman C
        • Dolson L
        • Kedar A
        Secretion of vasointestinal peptide by a primary liver tumour with rhabdoid features.
        J Surg Oncol. 1993; 54: 267-270
        • Di Cori S
        • Oudjhane K
        • Neilson K
        Primary malignant rhabdoid tumour of the liver.
        Can Assoc Radiol J. 1993; 44: 52-54
        • Pogacnik A
        • Zidar N
        Malignant rhabdoid tumour of the liver diagnosed by fine needle aspiration cytology. A case report.
        Acta Cytologica. 1997; 41: 539-543
        • Stringer MD
        • Hennayake S
        • Howard ER
        • et al.
        Improved outcome for children with hepatoblastoma.
        Br J Surg. 1995; 82: 386-391
        • Zhu LX
        • Wang GS
        • Fan ST
        Spontaneous rupture of hepatocellular carcinoma.
        Br J Surg. 1996; 83: 602-607