Abstract
The authors report a case of isolated imperforate anus with perineal fistula in monozygotic
twins. Only 4 other well-documented cases of monozygotic twins concordant for isolated
anorectal malformation have been reported in the literature. In all these cases the
defect occurred below the levator ani muscle. This case confirms previous reports
on the incidence of low anorectal anomalies in monozygotic twins where the defect
was isolated. A review of the literature relating to this condition in twins and siblings
points toward low anomalies and more severe malformations having different genetic
backgrounds.
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© 2005 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
