Inflammatory myofibroblastic tumor of renal pelvis presenting with prolonged fever and abdominal pain in children: report of 1 case and review of literature


      Inflammatory myofibroblastic tumor is a reactive proliferative lesion that occurs extremely rarely in the renal pelvis, especially during childhood. We report 1 such case that occurred in a child who presented with prolonged fever and abdominal pain. Ultrasonography and abdominal computed tomography revealed a left renal pelvic mass. She received conservative surgical treatment. The diagnosis was confirmed by pathological and immunohistochemical studies. Distinguishing inflammatory myofibroblastic tumor from other malignant renal pelvic tumors in children is essential to preventing unnecessary nephrectomy.

      Index words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of Pediatric Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Karnak I.
        • Senocak M.E.
        • Ciftci A.O.
        • et al.
        Inflammatory myofibroblastic tumor in children: diagnosis and treatment.
        J Pediatr Surg. 2001; 36: 908-912
        • Coffin C.M.
        • Watterson J.
        • Priest J.R.
        • et al.
        Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor): a clinicopathologic and immunohistochemical study of 84 cases.
        Am J Pathol. 1995; 19: 859-872
        • Kapusta L.R.
        • Weiss M.A.
        • Ramsay J.
        • et al.
        Inflammatory myofibroblastic tumors of the kidney: a clinicopathologic and immunohistochemical study of 12 cases.
        Am J Surg Pathol. 2003; 27: 658-666
        • Redondo E.
        • Rey Lopez A.
        • Rapariz Gonzalez M.
        • et al.
        Plasma-cell granuloma of the kidney pelvis.
        Arch Esp Urol. 2002; 55 ([French]): 85-87
        • Sugimoto K.
        • Hayashi T.
        • Imanishi M.
        • et al.
        A case of inflammatory pseudotumor of renal pelvis showing a complete response to antibiotics.
        Hinyokika Kiyo. 2004; 50: 629-631
        • Choi B.Y.
        • Kim W.S.
        • Cheon J.-E.
        • et al.
        Inflammatory myofibroblastic tumor of the liver in a child: CT and MR findings.
        Pediatr Radiol. 2003; 33: 30-33
        • Macfarlane M.T.
        • Stein A.
        • Layfield L.
        • et al.
        Preoperative endoscopic diagnosis of fibroepithelial polyp of the renal pelvis: a case report and review of the literature.
        J Urol. 1991; 145: 549-551
        • Yazaki T.
        • Satoh S.
        • Iizumi T.
        • et al.
        Solitary fibrous tumor of renal pelvis.
        Int J Urol. 2001; 8: 504-508
        • Uchida M.
        • Watanabe H.
        • Mishina T.
        • et al.
        Leiomyoma of the renal pelvis.
        J Urol. 1981; 125: 572-574
        • Arber D.A.
        • Kamel O.W.
        • van de Rijn M.
        • et al.
        Frequent presence of the Epstein Barr virus in inflammatory pseudotumor.
        Hum Pathol. 1995; 26: 1093-1098
        • Gomez-Roman J.J.
        • Sanchez-Velasco P.
        • Ocejo-Vinyals G.
        • et al.
        Human herpesvirus–8 genes are expressed in pulmonary inflammatory myofibroblastic tumor.
        Am J Surg Pathol. 2001; 25: 624-629
        • Morris S.W.
        • Kirstein M.N.
        • Valentine M.B.
        • et al.
        Fusion of a kinase gene, ALK, to a nucleolar protein gene. NPM, in non-Hodgkin's lymphoma.
        Science. 1994; 263: 1281-1284
        • Coffin C.M.
        • Patel A.
        • Perkins S.
        • et al.
        ALK1 and p80 expression and chromosomal rearrangements involving 2p23 in inflammatory myofibroblastic tumor.
        Mod Pathol. 2001; 14: 569-576
        • Chan J.K.C.
        • Cheuk W.
        • Shimizu M.
        • et al.
        Anaplastic lymphoma kinase expression in inflammatory pseudotumors.
        Am J Surg Pathol. 2001; 25: 761-768