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Mucormycosis is an opportunistic infection that has been mainly described in adults
with preexisting disease affecting immune status, eg, diabetes, leukemia, lymphoma,
and renal failure on peritoneal dialysis. Few cases have been described in neonates.
The presentation of mucormycosis as a cause of neonatal necrotizing enterocolitis
is an unusual phenomenon. Three fatal cases of mucormycosis of the gut in premature
infants in the period 1990 to 1991 are described. It is not clear whether this should
be considered a separate disease or a variant of necrotizing enterocolitis. All three
patients died soon after laparotomy from septic shock and the histological diagnosis
of mucormycosis was made too late for effective chemotherapy.
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Footnotes
*Presented at the 24th Annual Meeting of the Pacific Association of Pediatric Surgeons, Hong Kong, May 20–24, 1991.
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Copyright
© 1992 W.B. Saunders Company. All right reserved. Published by Elsevier Inc.
