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The frequency of necrotizing enterocolitis (NEC) in the extremely premature infant (<1,000 g) is still high and it is very difficult for infants weighing <1,000 g with NEC perforation to survive. In our institutes, the management protocol for NEC perforation in infants weighing <1,000 g includes peritoneal drainage under local anesthesia, administration of coagulating factor XIII, and the usual treatment for septic shock. During the past 3 years, four infants weighing <1,000 g with NEC perforation have survived using this protocol without laparotomy. This management protocol is the treatment of choice in infants in very poor condition or infants weighing <1,000 g with NEC perforation.
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*Presented at the 24th Annual Meeting of the Pacific Association of Pediatric Surgeons, Hong Kong, May 20–24, 1991.
© 1992 W.B. Saunders Company. All right reserved. Published by Elsevier Inc.