Abstract
Anomalous arrangement of the pancreaticobiliary duct is considered to be a high-risk
factor for biliary tract malignancy. We report a case of intrahepatic cholangiocarcinoma
in a 26-year-old man after total resection of choledochal cyst with anomalous arrangement
of the pancreaticobiliary duct at the age of 5 months. He had been doing well after
total resection of the choledochal cyst; however, he suddenly presented with a spiky
fever and abdominal pain in the right upper quadrant at the age of 26 years. Computed
tomographic scan and percutaneous transhepatic cholangioscope revealed multiple stones
and stenosis of the hepatic duct and the left intrahepatic bile duct. Histologic examination
of a biopsy specimen obtained from the stenotic site showed adenocarcinoma of the
intrahepatic bile duct. Left lobectomy with re-reconstruction by right hepaticojejunostomy
was performed, and his postoperative course was uneventful. One year after the operation,
however, he died of carcinomatous peritonitis with recurrence of cholangiocarcinoma.
This report warns us that bile stasis owing to stenosis of the intrahepatic bile duct
and repeated cholangitis with multiple stones are high-risk factors for carcinogenesis
of the intrahepatic bile duct even after total resection of the infantile choledochal
cyst.
Key words
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Article info
Publication history
Accepted:
January 28,
2008
Received in revised form:
January 28,
2008
Received:
August 23,
2007
Identification
Copyright
© 2008 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
