Abstract
Acute neonatal appendicitis is a rare condition associated with significant morbidity
and mortality. The severity of this disease is caused by its tendency to occur more
frequently in premature infants, an increased perforation rate with rapid progression
to peritonitis, and delay in diagnosis and intervention. Although appendicitis in
the perinatal period may occur as an isolated event, in many cases it occurs in association
with other pathologic states, including prematurity, inguinal hernia, and others.
The presentation of neonatal appendicitis can be identical to necrotizing enterocolitis,
leading to misdiagnosis. Here we report a case of perforated appendicitis in a 9-day-old
boy with tetralogy of Fallot and esophageal atresia with tracheoesophageal fistula.
In addition, we present a review of the clinical features of neonatal appendicitis
and a discussion of previously described, associated conditions.
Key words
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of Pediatric SurgeryAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Seven cases of neonatal appendicitis with a review of the English language literature of the last century.Pediatr Surg Int. 2003; 19: 707-709
- Neonatal appendicitis masquerading as necrotizing enterocolitis.J Pediatr. 1980; 96: 917-918
- Appendicitis in infancy.Pediatr Surg Int. 2003; 19: 1-3
- Acute appendicitis in neonates: complication or morbus sui generis?.Pediatr Surg Int. 1998; 14: 122-123
- Perforation of the appendix in the neonatal period.J Pediatr Surg. 1980; 15: 200-202
- Neonatal appendicitis mistaken for necrotizing enterocolitis.South Med J. 1982; 75: 1155
- Neonatal acute appendicitis: a strangulated appendix in an incarcerated inguinal hernia.Pediatr Surg Int. 2001; 17: 644-645
- Neonatal appendicitis: ischemic infarction in incarcerated inguinal hernia.J Pediatr Surg. 1978; 13: 177-179
- Acute appendicitis in a premature baby.Eur Radiol. 2002; 12: S152-S154
- Further evidence for an ischemic origin of perforation of the appendix in the neonatal period.J Pediatr Surg. 2004; 39: e11-e12
- Neonatal appendiceal perforation and Hirschsprung's disease.J Pediatr Surg. 1990; 25: 694-695
- Acute appendicitis presenting as gastroenteritis in an infant.Br J Clin Pract. 1973; 27: 21-22
- Neonatal perforation of the appendix in association with Hirschsprung's disease.Ann Surg. 1967; 166: 799-802
- Appendiceal mass in a neonate after surgery for esophageal atresia and tracheoesophageal fistula: report of a case.Surg Today. 2005; 35: 80-81
- Perforation of the appendix from intestinal mucormycosis in a neonate.J Pediatr Surg. 2004; 39: 1133-1135
- Fatal neonatal perforation of appendix.Indian Pediatr. 1989; 26: 1166-1167
- Appendicular perforation in necrotising enterocolitis.Indian Pediatr. 1998; 35: 59-61
- Cytomegalovirus enterocolitis complicated by perforated appendicitis in a premature infant.J Pediatr Surg. 2006; 41: 1476-1478
- Appendiceal peritonitis and megacolon in the neonatal period.Acta Chir Scand. 1970; 136: 153-155
- Perforated appendicitis in a newborn infant associated with Down's syndrome. Review of the literature.Pediatr Med Chir. 1986; 8: 113-114
- Acute appendicitis in the first two years of life.J Pediatr Surg. 1973; 8: 285-293
- Neonatal pyoscrotum and perforated appendicitis.J Perinatol. 1999; 19: 536-537
- Acute appendicitis with fulminant necrotizing fasciitis in a neonate.J Pediatr Surg. 2003; 38: E5-E6
- Perforated acute appendicitis in a term neonate.Indian J Pediatr. 2004; 71: 357-358
- Appendicitis with perforation in a 12-day-old infant.Can Med Assoc J. 1966; 94: 447-448
- Acute perforated neonatal appendicitis associated with chorioamnionitis.Eur J Pediatr Surg. 2001; 11: 204-206
- Radiological case of the month. Neonatal appendicitis with perforation.Am J Dis Child. 1991; 145: 111-112
- Fatal postoperative acute appendicitis in a neonate with congenital heart disease.J Pediatr Surg. 1981; 16: 85-86
- Congenital ureteropelvic junction obstruction associated with unsuspected acute perforated appendicitis in a neonate.J Urol. 1978; 120: 247-248
Article info
Publication history
Accepted:
May 2,
2008
Received in revised form:
April 25,
2008
Received:
January 29,
2008
Identification
Copyright
© 2008 Elsevier Inc. Published by Elsevier Inc. All rights reserved.