Abstract
Anorectal malformation (ARM) can be divided in high, intermediate, and low forms according
to the level of termination of the rectum in relation to the pubococcygeal and ischiatic
lines. Patients with Down's syndrome have a high incidence of gastrointestinal anomalies,
such as tracheoesophageal fistula, duodenal obstruction, annular pancreas, Hirschsprung's
disease, and ARM. In these children, ARM is generally low with or without a fistula.
The mode of inheritance of ARM and its genetic relation with Down's syndrome is not
known, even if the association (ARM-Down's syndrome) seems not to be coincidental.
We describe here a very rare case of monozygotic twins born with the association of
ARM and Down's syndrome.
Key words
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Article info
Publication history
Accepted:
October 30,
2008
Received in revised form:
October 29,
2008
Received:
August 17,
2008
Identification
Copyright
© 2009 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
