Advertisement
Original article| Volume 46, ISSUE 9, P1700-1705, September 2011

Acute to chronic postoperative pain in children: preliminary findings

  • Michelle A. Fortier
    Correspondence
    Corresponding author. CHOC Children's Hospital, Orange, CA 92868, USA. Tel.: +1 714 480 0067; fax: +1 714 480 0733.
    Affiliations
    Department of Anesthesiology and Perioperative Care, University of California-Irvine, Orange, CA 92868, USA

    Department of Pediatric Psychology, CHOC Children's Hospital, Orange, CA 92868, USA
    Search for articles by this author
  • Jody Chou
    Affiliations
    Department of Anesthesiology and Perioperative Care, University of California-Irvine, Orange, CA 92868, USA
    Search for articles by this author
  • Eva L. Maurer
    Affiliations
    Department of Anesthesiology and Perioperative Care, University of California-Irvine, Orange, CA 92868, USA
    Search for articles by this author
  • Zeev N. Kain
    Affiliations
    Department of Anesthesiology and Perioperative Care, University of California-Irvine, Orange, CA 92868, USA

    Departments of Pediatrics and Psychiatry and Human Behavior, University of California-Irvine, Orange, CA 92868, USA

    Department of Pediatrics, CHOC Children's Hospital, Orange, CA 92868, USA
    Search for articles by this author

      Abstract

      Background/purpose

      Chronic postoperative pain is a well-established clinical phenomenon that is associated with adverse outcomes. The incidence of this clinical phenomenon in children, however, is not well established. The purpose of this study was to identify the incidence of chronic pain in children after surgery.

      Methods

      Following a screening process, a total of 113 children and their parents were enrolled in this cross-sectional study. Data regarding persistence and characteristics of pain after surgery were obtained.

      Results

      Approximately 13% of the children, most of whom underwent orthopedic procedures, reported the existence of symptoms of chronic postoperative pain. Most of the children indicated that the pain started immediately after surgery, was localized to the surgery site, and was intermittent. Children reported a median duration of pain of 4.1 months, and approximately half of the children experienced pain most days of the week. Up to 30% of the children reported interference of pain in functioning in areas such as extracurricular activities and sleep.

      Discussion

      Given the large number of children at risk for experiencing chronic postoperative pain, preventative efforts are necessary. Large-scale cohort prospective studies are needed to confirm the results of this cross-sectional study.

      Key words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Pediatric Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Kehlet H.
        • Jensen T.S.
        • Woolf C.
        Persistent postsurgical pain: risk factors and prevention.
        Lancet. 2006; 367: 1618-1625
        • Macrae W.A.
        Chronic post-surgical pain: 10 years on.
        Br J Anaesth. 2008; 101: 77-86
        • Shipton E.
        Predictors of persistent acute postoperative pain: an opportunity for preventative medicine to reduce the burden of chronic pain.
        N Z Med J. 2005; 118: U1261
        • Macrae W.A.
        Chronic pain after surgery.
        Br J Anaesth. 2001; 87: 88-98
        • Perkins F.M.
        • Kehlet H.
        Chronic pain as an outcome of surgery: a review of predictive factors.
        Anesthesiology. 2000; 93: 1123-1133
        • Aasvang E.
        • Kehlet H.
        Chronic postoperative pain: the case of inguinal herniorrhaphy.
        Br J Anaesth. 2005; 95: 69-76
        • Aasvang E.K.
        • Bay-Nielsen M.
        • Kehlet H.
        Pain and functional impairment 6 years after inguinal herniorrhaphy.
        Hernia. 2006; 10: 316-321
        • Maguire M.F.
        • Ravenscroft A.
        • Beggs D.
        • et al.
        A questionnaire study investigating the prevalence of the neuropathic component of chronic pain after thoracic surgery.
        Eur J Cardiothorac Surg. 2006; 29: 800-805
        • Reuben S.
        • Yalavarthy L.
        Preventing the development of chronic pain after thoracic surgery.
        J Cardiothorac Vasc Anesth. 2008; 22: 890-903
        • Fassoulaki A.
        • Melemeni A.
        • Staikou C.
        • et al.
        Acute postoperative pain predicts chronic pain and long-term analgesic requirements after breast surgery for cancer.
        Acta Anaesthesiol Belg. 2008; 59: 241-248
        • Vilholm O.J.
        • Cold S.
        • Rasmussen L.
        • et al.
        The postmastectomy pain syndrome: an epidemiological study on the prevalence of chronic pain after surgery for breast cancer.
        Br J Cancer. 2008; 99: 604-610
        • Hanley M.A.
        • Jensen M.P.
        • Smith D.G.
        • et al.
        Preamputation pain and acute pain predict chronic pain after lower extremity amputation.
        J Pain. 2007; 8: 102-109
        • Nikolajsen L.
        • Jensen T.
        Phantom limb pain.
        Curr Rev Pain. 2000; 4: 166-170
        • Nikolajsen L.
        • Sorensen H.
        • Jensen T.
        • et al.
        Chronic pain following caesarian section.
        Acta Anaesthesiol Scand. 2004; 48: 111-116
        • Flor H.
        Phantom-limb pain: characteristics, causes, and treatment.
        Lancet Neurol. 2002; 1: 182-189
        • Hunfeld J.A.
        • Perquin C.W.
        • Duivenvoorden H.J.
        • et al.
        Chronic pain and its impact on quality of life in adolescents and their families.
        J Pediatr Psychol. 2001; 26: 145-153
        • Midence K.
        The effects of chronic illness on children and their families: an overview.
        Genet Soc Gen Psychol Monogr. 1994; 120: 309-326
        • Roth-Isigkeit A.
        • Thyen U.
        • Stöven H.
        • et al.
        Pain among children and adolescents: restrictions in daily living and triggering factors.
        Pediatrics. 2005; 115: 152-162
        • Stang P.
        • Osterhaus J.
        Impact of migraine in the United States: data from the National Health Interview Survey.
        Headache. 1993; 33: 29-35
        • Conte P.M.
        • Walco G.A.
        • Kimura Y.
        Temperament and stress response in children with juvenile primary fibromyalgia syndrome.
        Arthritis Rheum. 2003; 48: 2923-2930
        • Konijnenberg A.Y.
        • Uiterwaal C.S.
        • Kimpen J.L.
        • et al.
        Children with unexplained chronic pain: substantial impairment in everyday life.
        Arch Dis Child. 2005; 90: 680-686
        • Walker L.
        • Greene J.
        Children with recurrent abdominal pain and their parents: more somatic complaints, anxiety, and depression than other patient families?.
        J Pediatr Psychol. 1989; 14: 231-243
        • Schanberg L.E.
        • Anthony K.K.
        • Gil K.M.
        • et al.
        Daily pain and symptoms in children with polyarticular arthritis.
        Arthritis Rheum. 2003; 48: 1390-1397
        • Schanberg L.E.
        • Sandstrom M.J.
        • Starr K.
        • et al.
        The relationship of daily mood and stressful events to symptoms in juvenile rheumatic disease.
        Arthritis Care Res. 2000; 13: 33-41
        • Joshi G.P.
        • Ogunnaike B.O.
        Consequences of inadequate postoperative pain relief and chronic persistent postoperative pain.
        Anesthesiol Clin North America. 2005; 23: 21-36
        • Kain Z.N.
        • Mayes L.C.
        • O'Connor T.Z.
        • et al.
        Preoperative anxiety in children. Predictors and outcomes.
        Arch Pediatr Adolesc Med. 1996; 150: 1238-1245
        • Green C.R.
        • Anderson K.O.
        • Baker T.A.
        • et al.
        The unequal burden of pain: confronting racial and ethnic disparities in pain.
        Pain Med. 2003; 4: 277-294
        • Edwards R.R.
        • Doleys D.M.
        • Fillingim R.B.
        • et al.
        Ethnic differences in pain tolerance: clinical implications in a chronic pain population.
        Psychosom Med. 2001; 63: 316-323
        • Cintron A.
        • Morrison R.S.
        Pain and ethnicity in the United States: a systematic review.
        J Palliat Med. 2006; 9: 1454-1473
        • Fillingim R.
        Individual differences in pain responses.
        Curr Rheumatol Rep. 2005; 7: 342-347
        • Widmalm S.E.
        • Christiansen R.L.
        • Gunn S.M.
        Race and gender as TMD risk factors in children.
        Cranio. 1995; 13: 163-166
        • Jacob E.
        • McCarthy K.S.
        • Sambuco G.
        • et al.
        Intensity, location, and quality of pain in Spanish-speaking children with cancer.
        Pediatr Nurs. 2008; 34: 45-52
        • Abu-Saad H.
        Cultural components of pain: the Arab-American child.
        Issues Compr Pediatr Nurs. 1984; 7: 91-99
        • Abu-Saad H.
        Cultural components of pain: the Asian-American child.
        Child Health Care. 1984; 13: 11-14
        • Duggleby W.
        Helping Hispanic/Latino home health patients manage their pain.
        Home Healthc Nurse. 2003; 21: 174-179
        • McNeill J.A.
        • Sherwood G.
        • Starck P.
        • et al.
        Design strategies in pain management research with Hispanics.
        Hispanic Health Care Int. 2003; 2: 73-80