Advertisement
Rapid Communication| Volume 48, ISSUE 1, e1-e3, January 2013

Toxic shock syndrome due to group A beta-hemolytic streptococcus presenting with purpura fulminans and limb ischemia in a pediatric patient treated with early microsurgical arteriolysis

DOI:https://doi.org/10.1016/j.jpedsurg.2012.09.057
Toxic shock syndrome due to group A beta-hemolytic streptococcus presenting with purpura fulminans and limb ischemia in a pediatric patient treated with early microsurgical arteriolysis
Previous ArticleAnnouncements of Future Meetings
Next ArticleMultiple urethral anomalies: Anterior urethral diverticulum, posterior urethral valves, and distal hypospadias

      Abstract

      We describe a 2.5 year-old child with toxic shock syndrome due to group A beta-hemolytic streptococcus (GABHS) who presented with purpura fulminans and limb ischemia treated with early microsurgical arteriolysis. The clinical picture of toxic shock syndrome (TSS) presenting with purpura fulminans and limb ischemia is an exceptionally uncommon finding in sepsis due to GABHS. This is the first case of purpura fulminans caused by GABHS reported in Europe and the third one described in the literature (Dhodapkar et al., 2000[
      • Dhodapkar K.
      • Corbacioglu S.
      • Chang M.W.
      • et al.
      Purpura fulminans caused by group A beta-hemolytic streptococcus sepsis.
      J Pediatr. 2000; 137: 562-567
      ]; Renaud et a., 2011[
      • Renaud C.
      • Ovetchkine P.
      • Bortolozzi P.
      • et al.
      Fatal group A streptococcus purpura fulminans in a child receiving TNF-a blocker.
      Eur J Pediatr. 2011; 170: 657-660
      ]).

      Key words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Pediatric Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Register: Create an account
      Institutional Access: Sign in to ScienceDirect

      References

        • Dhodapkar K.
        • Corbacioglu S.
        • Chang M.W.
        • et al.
        Purpura fulminans caused by group A beta-hemolytic streptococcus sepsis.
        J Pediatr. 2000; 137: 562-567
        View in Article
        • Renaud C.
        • Ovetchkine P.
        • Bortolozzi P.
        • et al.
        Fatal group A streptococcus purpura fulminans in a child receiving TNF-a blocker.
        Eur J Pediatr. 2011; 170: 657-660
        View in Article
        • Piepmeier Jr., E.
        • Hamett-Stabler C.
        • Price M.
        • et al.
        Myositis and fasciitis associated with group A beta hemolytic streptococcal infections: development of a rabbit model.
        J Lab Clin Med. 1995; 126: 137-143
        View in Article
        • Pichichero M.E.
        Group A beta-hemolytic streptococcal infections.
        Pediatr Rev. 1998; 19: 291-302
        View in Article
        • Khan Z.Z.
        • Salvaggio M.R.
        • Sharma S.
        • et al.
        Streptococcus group A infections: eMedicine infectious diseases.
        http://emedicine.medscape.com/article/228936-overview
        (last accessed: July 25th, 2009)
        View in Article
        • Sharma Sat
        Toxic shock syndrome: eMedicine critical care.
        http://emedicine.medscape.com/article/169177-overview
        (last accessed: July 25th, 2009)
        View in Article
        • Schurr M.
        • Engelhardt S.
        • Helgerson R.
        Limb salvage for streptococcal gangrene of the extremity.
        Am J Surg. 1998; 175: 213-217
        View in Article
        • Boeckx W.D.
        • Nanhekhan L.
        • Vos G.D.
        • et al.
        Minimizing limb amputations in meningococcal sepsis by early microsurgical arteriolysis.
        J Pediatr Surg. 2009; 44: 1625-1630
        View in Article

      Article info

      Publication history

      Accepted: September 10, 2012
      Received in revised form: August 19, 2012
      Received: February 27, 2012

      Identification

      DOI: https://doi.org/10.1016/j.jpedsurg.2012.09.057

      Copyright

      © 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

      ScienceDirect

      Access this article on ScienceDirect
      We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the for this site.
      Copyright © 2023 Elsevier Inc. except certain content provided by third parties. The content on this site is intended for healthcare professionals.


      RELX