Abstract
Breast enlargement in prepubertal boys is a rare condition. This case report describes
an otherwise healthy 3-year old non-obese boy who developed a large unilateral cystic
breast mass measuring approximately 9 × 6 × 4 cm. The mass was initially treated as a lymphatic malformation, and sclerotherapy
with Picibanil® (OK-432) was attempted without any detectable effect on size. The
mass was later excised. The pathological examination revealed mammary gland tissue
suggestive of idiopathic gynecomastia. FISH revealed 47, XXY mosaicism in the abnormal
breast epithelial cells, but not in peripheral blood lymphocytes.
Key words
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Article info
Publication history
Accepted:
November 17,
2012
Received in revised form:
November 15,
2012
Received:
July 18,
2012
Identification
Copyright
© 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
