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Rhabdomyosarcoma in adrenal region of a child with hypertension and fever: A case report and literature review

      Abstract

      Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children but rarely involves the adrenal. We describe a case of alveolar rhabdomyosarcoma (ARMS) of the right adrenal in a 5-year-old boy with a characteristic history of hypertension and recurrent fever. On surveillance imaging, a right adrenal mass was incidentally detected, and a right adrenalectomy was subsequently performed. After the surgery, the fever disappeared simultaneously, and the blood pressure gradually returned to normal level. This is the first reported case in children.

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      References

        • Perez E.A.
        • Kassira N.
        • Cheung M.C.
        • et al.
        Rhabdomyosarcoma in children: a SEER population based study.
        J Surg Res. 2011; 170: e243-e251
        • Katayama A.
        • Otsuka F.
        • Takeda M.
        • et al.
        Rhabdomyosarcoma discovered in the adrenal region of an elderly hypertensive patient.
        Hypertens Res. 2011; 34: 784-786
        • Dagher R.
        • Helman L.
        Rhabdomyosarcoma: an overview.
        Oncologist. 1999; 4: 34-44
        • Charytonowicz E.
        • Cordon-Cardo C.
        • Matushansky I.
        • et al.
        Alveolar rhabdomyosarcoma: is the cell of origin a mesenchymal stem cell?.
        Cancer Lett. 2009; 279: 126-136
        • Parham D.M.
        • Ellison D.A.
        Rhabdomyosarcomas in adults and children: an update.
        Arch Pathol Lab Med. 2006; 130: 1454-1465
        • Breitfeld P.P.
        • Meyer W.H.
        Rhabdomyosarcoma: new windows of opportunity.
        Oncologist. 2005; 10: 518-527
        • Weihkopf T.
        • Blettner M.
        • Dantonello T.
        • et al.
        Incidence and time trends of soft tissue sarcomas in German children 1985–2004 — a report from the population-based German Childhood Cancer Registry.
        Eur J Cancer. 2008; 44: 432-440
        • Pennacchioli E.
        • Fiore M.
        • Collini P.
        • et al.
        Alveolar soft part sarcoma: clinical presentation, treatment, and outcome in a series of 33 patients at a single institution.
        Ann Surg Oncol. 2010; 17: 3229-3233
        • Caoili E.M.
        • Korobkin M.
        • Francis I.R.
        • et al.
        Adrenal masses: characterization with combined unenhanced and delayed enhanced CT.
        Radiology. 2002; 222: 629-633
        • Forgie S.E.
        • Robinson J.L.
        Pediatric malignancies presenting as a possible infectious disease.
        BMC Infect Dis. 2007; 7: 44