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Rapid Communication| Volume 48, ISSUE 4, e5-e8, April 2013

Clostridium septicum gas gangrene in a previously healthy 8-year-old female with survival

      Abstract

      We present the only reported case of an immunocompetent pediatric patient in the literature to have fulminate gas gangrene of the lower extremity and concomitant gastrointestinal tract infection due to Clostridium septicum coinfected with Clostridium difficile colitis respectively. The patient survived with aggressive medical and surgical treatment.

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      References

        • Foga M.M.
        • Foga M.M.
        • McGinn G.J.
        • et al.
        Sepsis due to Clostridium septicum: case report.
        Can Assoc Radiol J. 2000; 51: 85-89
        • Corey E.C.
        Nontraumatic gas gangrene: case report and review of emergency therapeutics.
        J Emerg Med. 1991; 9: 431-436
        • Dylewski J.
        • Drummond R.
        • Rowen J.
        A case of Clostridium septicum spontaneous gas gangrene.
        CJEM. 2007; 9: 133-135
        • Pelfrey T.M.
        • Turk R.P.
        • Peoples J.B.
        • et al.
        Surgical aspects of Clostridium septicum septicemia.
        Arch Surg. 1984; 119: 546-550
        • Aggelidakis J.
        • Lasithiotakis K.
        • Topalidou A.
        • et al.
        Limb salvage after gas gangrene: a case report and review of the literature.
        World J Emerg Surg. 2011; 6: 28
        • Henderson D.K.
        Infectious disease emergencies: the clostridial syndromes. Botulism.
        West J Med. 1978; 129: 101-106
        • Barlett J.G.
        Clostridium difficile infection pathophysiology and diagnosis.
        Semin Gastrointest Dis. 1997; 8: 12-21
        • Feltis B.A.
        • Kim A.S.
        • Kinnerberg K.M.
        • et al.
        Clostridium difficile toxins may augment bacterial penetration of intestinal epithelium.
        Arch Surg. 1999; 134: 1235-1242
        • Smith-SLatus Candra L.
        • Bourque Michael
        • Salazar Juan C.
        Clostridium septicum infections in children: a case report and review of the literature.
        Pediatrics. 2006; 117: e796-e805
        • Robert E.
        • Schaaf M.D.
        • Kelvin F.M.
        • et al.
        Clostridium septicum infection associated with colonic carcinoma and hematologic abnormality.
        Radiology. 1980; 137: 625-627
      1. Gnerlich JL, Ritter JH, Kirby JP, Mazuski JE Surg Infect (Larchmt). Simultaneous necrotizing soft tissue infection and colonic necrosis caused by Clostridium septicum. 2011 Dec;12(6):501–6. [Epub 2011 Dec 5].

        • Hunley T.E.
        • Spring M.D.
        • Peters T.R.
        • et al.
        Clostridium septicum myonecrosis complicating diarrhea associated hemolytic uremic syndrome.
        Pediatr Nephrol. 2008; 23: 1171-1175