Research Article| Volume 48, ISSUE 6, P1454-1457, June 2013

Topical Mitomycin C application for esophageal stricture: Safe, precise, and novel endoscopic technique



      The first line of management of benign esophageal stricture is endoscopic dilatation; however, multiple sessions are usually indicated especially in resistant cases. Topical Mitomycin C (MCC) application is a new adjuvant treatment in the management of esophageal stricture with promising results in different case series. Several techniques have been reported for application; nevertheless, the ideal technique has not been described yet.

      Material and Methods

      In this series we have devised a new technique using both the flexible and the rigid endoscope and a specially designed Nelaton catheter.


      This technique was applied in 38 sessions for 16 caustic esophageal strictures with technical success in all cases. No procedure-related complications were observed in this series.


      This novel technique is feasible and effective and can be considered as standard for topical MMC application on esophageal stricture.


      MMC (Mitomycin C)

      Key words

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