Abstract
Background
The European consortium on anorectal malformations (ARM-NET) was established to improve
the health care of patients and to identify genetic and environmental risk factors.
The aim of the present study was to present the first results on clinical data of
a large European cohort of ARM patients based on our registry.
Methods
In 2010, the registry was established including patient characteristics and data on
diagnosis, surgical therapy, and outcome regarding complications. Patients born between
2007 and 2012 were retrospectively added. A descriptive analysis of this cohort was
performed.
Results
Two hundred and three ARM patients were included. Syndromes or chromosomal abnormalities
were present in 9%. Perineal fistulas were seen most in boys (42%) and girls (29%).
Rare forms of ARM were found in 4% of the male and in 14% of the female patients.
Forty-five percent of the patients had additional urogenital abnormalities. However,
32% of the patients were never screened for bladder abnormalities. Eight percent were
never screened for renal malformations. In the majority of patients (79%), a PSARP
was performed for the definitive reconstruction.
Conclusion
This collaborative effort provides a representative basis to estimate incidence of
ARM types, to discuss differences and similarities in treatment, and health consequences
throughout Europe.
Key words
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Article info
Publication history
Accepted:
July 25,
2013
Received in revised form:
July 24,
2013
Received:
March 24,
2013
Identification
Copyright
© 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
