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Research Article| Volume 56, ISSUE 11, P1918-1925, November 2021

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The multidisciplinary management of recurrent tracheoesophageal fistula after esophageal atresia: Experience with 135 cases from a tertiary center

  • Author Footnotes
    † These authors contributed equally to this manuscript.
    Minzhong Zhang
    Footnotes
    † These authors contributed equally to this manuscript.
    Affiliations
    Department of Pediatric General Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Road, Shanghai, 200092, China

    Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, No. 1665, Kongjiang Road, Shanghai, 200092, China
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  • Author Footnotes
    † These authors contributed equally to this manuscript.
    Yangwen Lin
    Footnotes
    † These authors contributed equally to this manuscript.
    Affiliations
    Department of Pediatric General Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Road, Shanghai, 200092, China
    Search for articles by this author
  • Wei Xie
    Affiliations
    Department of Pediatric Intensive Care, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Road, Shanghai, 200092, China
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  • Juming Yu
    Affiliations
    Department of Interventional Radiology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Road, Shanghai, 200092, China
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  • Qi Huang
    Affiliations
    Department of Otolaryngology and Neck and Head Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Road, Shanghai, 200092, China
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  • Jing Li
    Affiliations
    Department of Pediatric Pulmonary Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Road, Shanghai, 200092, China
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  • Weihui Yan
    Affiliations
    Department of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Road, Shanghai, 200092, China

    Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, No. 1665, Kongjiang Road, Shanghai, 200092, China
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  • Jun Wang
    Correspondence
    Corresponding author.
    Affiliations
    Department of Pediatric General Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, No. 1665, Kongjiang Road, Shanghai, 200092, China
    Search for articles by this author
  • Author Footnotes
    † These authors contributed equally to this manuscript.

      Abstract

      Background & aims

      Recurrent tracheoesophageal fistula (rTEF) after esophageal atresia requires complex management across different specialties. This study reviews our experience and discusses a multidisciplinary (MDT) approach adopted in the past 4 years.

      Methods

      We reviewed the medical records of 100 patients with rTEF managed by an MDT approach (post-MDT group) from 2016 to 2019. These cases were compared to a historical group of 35 patients with rTEF from 2012 to 2015 (pre-MDT group).

      Results

      Of the 135 patients with rTEF, 124 were referred from other hospitals. Preoperative examination found tracheomalacia in 23 patients, vocal fold immobility in 19 patients, and laryngomalacia in five patients. The incidence of postoperative anastomotic leak, anastomotic stricture, and repeat recurrences was 28.1%, 23.0%, and 8.9%, respectively. The overall mortality rate was 4.4%. No statistical difference in postoperative complications was noted between the two groups. The duration of stay in the pediatric intensive care unit (P = 0.038), the duration of intubation (P = 0.049), the postoperative hospital stay (P = 0.011), and the total length of hospital stay (P = 0.001) were significantly lower in the post-MDT group. Mid-term follow-up showed 23 patients had pathological gastroesophageal reflux. Five of them underwent fundoplication and recovered.

      Conclusion

      The MDT approach by fostering coordination of surgical, medical, radiological, and nutritional management is beneficial in the management of rTEF and leads to a satisfactory outcome .

      Keywords

      Abbreviations:

      rTEF (recurrent tracheoesophageal fistula), EATEF (esophageal fistula with tracheoesophageal fistula), GER (gastroesophageal reflux), MDT (multidisciplinary), DOS in PICU (duration of stay in the pediatric intensive care unit), LOS (total length of hospital stay), NG (naso-gastric), NJ (naso-jejunal), POD (postoperative day), AS (anastomotic stenosis), AL (anastomotic leak), CI (confidence interval)
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