Gallbladder disease (GBD) has become increasingly common in children. Established
risk factors for GBD in childhood include hemolytic disease; ileal resections; obesity;
cystic fibrosis; and the use of parenteral nutrition, ceftriaxone, and oral contraceptives.
Notably, patients with cystic fibrosis (CF) face an increased risk of developing a
wide range of CF-related conditions, including a significantly greater odds ratio
for conditions such as cholelithiasis [
[1]
,
- Miller A.C.
- Comellas A.P.
- Hornick D.B.
- et al.
Cystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related
conditions.
Proc Natl Acad Sci U S A. 2020; 117 (Jan 21Epub 2019 Dec 27. PMID: 31882447; PMCID: PMC6983448): 1621-1627https://doi.org/10.1073/pnas.1914912117
[2]
]. Furthermore, surgeons should be aware of the high possibility of encountering a
difficult gallbladder operation in these patients.- Doud A.
- Bond L.
- Downard C.
- et al.
Management of complicated biliary disease in the pediatric population.
Surgery. 2022; 171 (MarEpub 2021 Nov 27. PMID: 34844759): 736-740https://doi.org/10.1016/j.surg.2021.09.041
Abbreviations:
GBD (gallbladder disease), CF (cystic fibrosis), LC (laparoscopic cholecystectomy), SLC (subtotal laparoscopic cholecystectomy)To read this article in full you will need to make a payment
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References
- Cystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related conditions.Proc Natl Acad Sci U S A. 2020; 117 (Jan 21Epub 2019 Dec 27. PMID: 31882447; PMCID: PMC6983448): 1621-1627https://doi.org/10.1073/pnas.1914912117
- Management of complicated biliary disease in the pediatric population.Surgery. 2022; 171 (MarEpub 2021 Nov 27. PMID: 34844759): 736-740https://doi.org/10.1016/j.surg.2021.09.041
- Predicting the difficult laparoscopic cholecystectomy based on a preoperative scale.Updates Surg. 2022; (Feb 4Epub ahead of print. PMID: 35122205)https://doi.org/10.1007/s13304-021-01216-y
- Safe laparoscopic subtotal cholecystectomy in the face of severe inflammation in the cystohepatic triangle: a retrospective review and proposed management strategy for the difficult gallbladder.Can J Surg. 2019 Dec 1; 62 (PMID: 31782296; PMCID: PMC6877394): 402-411https://doi.org/10.1503/cjs.014617
- Subtotal cholecystectomy for difficult acute cholecystitis: how to finalize safely by laparoscopy-a systematic review.World J Emerg Surg. 2021; 16 (Sep 8PMID: 34496916; PMCID: PMC8424983): 45https://doi.org/10.1186/s13017-021-00392-x
Article info
Publication history
Published online: April 21, 2022
Accepted:
April 13,
2022
Received:
April 7,
2022
Identification
Copyright
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