- •In a retrospective, single-institution study, patients with perforated appendicitis were evaluated for post-discharge antibiotic efficacy in reducing deep-space infections.
- •We found no difference in ED visits, readmissions, or organ-space infections between the two groups.
- •Although the numbers were small, the study also raised questions as to whether patients with a known postoperative abscess benefited from additional oral antibiotics after discharge.
Aim of the study
Level of evidence
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
- Perforation risk in pediatric appendicitis: assessment and management.Pediatric Health Med Ther. 2018; 9: 135-145
- Trends in appendicitis and perforated appendicitis prevalence in children in the United States, 2001-2015.JAMA Netw Open. 2020; 3
- Rate of pediatric appendiceal perforation at a children's hospital during the COVID-19 pandemic compared with the previous year.JAMA Netw Open. 2020; 3
- Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem.Ther Adv Drug Saf. 2014; 5: 229-241
- Standardized discharge antibiotics may reduce readmissions in pediatric perforated appendicitis.J Surg Res. 2020; 255: 388-395
- An evidence-based care protocol improves outcomes and decreases cost in pediatric appendicitis.J Surg Res. 2020; 256: 390-396
- The utility of discharge antibiotics in pediatric perforated appendicitis without leukocytosis.J Surg Res. 2022; 275: 48-55
- Oral antibiotics and abscess formation after appendectomy for perforated appendicitis in children.J Surg Res. 2020; 256: 56-60
- Standardized care and oral antibiotics on discharge for pediatric perforated appendicitis.J Surg Res. 2021; 267: 717-718
- Risk stratification in pediatric perforated appendicitis: prospective correlation with outcomes and resource utilization.J Pediatr Surg. 2018; 53: 250-255