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Genetic variants in pectus excavatum

      Pectus Excavatum (PEx) is the most common congenital chest wall deformity (incidence 1:400 white Caucasian males) [
      • Chung C.S.
      • Myrianthopoulos N.C.
      Factors affecting risks of congenital malformations. I. Analysis of epidemiologic factors in congenital malformations.
      ]. This disease often manifests during adolescence with growth, leading to underdiagnosis especially in women owing to development of breast tissue. Many patients present as adults, highly symptomatic from cardiopulmonary compromise.
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